What are some strategies to reduce taxable income?

Top strategies include maximizing pre-tax retirement contributions (401k, traditional IRA, SEP-IRA), contributing to an HSA if you have a high-deductible health plan, taking above-the-line deductions for student loan interest and self-employed health insurance, and deferring business income to the next year if you expect to be in a lower bracket. Each dollar shifted to tax-advantaged accounts directly reduces your AGI.